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Adult: Initial dosage: 25 mg 2 times daily for the first 2-4 days; increase to 25 mg 4 times daily for balance of the first week.
Dosage titration: 50 mg 4 times daily from the second week on.
Maintenance dosage: Adjust dosage to the lowest effective levels. Up to 300 mg/day may be required in resistant patients.
Mode of Administration: Administered without regard to meals. However, food enhances bioavailability; administer consistently with regard to meals.
